Cordelia L. Knox was the daughter of Sarah Ann Curtis and John Jay Knox. She was born on 14 August 1817 in Augusta, Oneida, New York. Cordelia was the second of ten children.
Cordelia married Andrew Anderson on 23 May 1843. Cordelia and Andrew had six children.
Cordelia died on 10 Jan 1876 in Brooklyn, New York, just one year after her mother died. She is buried in Woodlawn Cemetery in the Bronx, New York.